2026年9月18日-20日，世界华人医师年会暨“以科技创新优化医疗场景”高峰论坛隆重召开，大会现场颁发第九届“世界杰出华人医师霍英东奖”。美国密歇根大学骆淑芳（Anna S.F. Lok）教授凭借在病毒性肝炎领域数十年的开创性研究与全球公共卫生贡献获此殊荣。这份荣誉，既是对她深耕肝病研究、推动全球肝病诊疗进步的高度肯定，也是华人医师在国际肝病学界卓越影响力的有力彰显。此外，本次会上骆淑芳教授作了题为《肝病医生的成长——从临床卓越到科研创新》的报告，本刊借此契机对骆淑芳教授展开专访，围绕临床与科研的辩证关系、青年医师培养等行业关切话题进行对话，希望能为广大肝病从业者带来启发与借鉴。

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《国际肝病》：祝贺您荣获“世界杰出华人医师霍英东奖”。获得这项荣誉，您有怎样的感想，它对您而言意味着什么？回望您的成长历程，哪一个临床观察或患者故事真正促使您从“解决个体患者问题”走向“设计研究、改变群体实践”？您如何理解“临床卓越”与“科研创新”之间的关系？

骆淑芳教授：首先，我非常荣幸能够获此奖项。这份荣誉是对我数十年工作的肯定，也离不开众多同仁的支持，正是大家的助力，才成就了我如今的职业道路。

其实并非某一位特定的患者故事启发了我的研究。我选择乙肝作为研究方向，根源在于这种疾病给中国人群带来沉重疾病负担。我早年在香港开启职业生涯时，目睹太多患者正值壮年却饱受乙肝相关肝硬化和肝癌的折磨。这促使我想要深入认识这一疾病，更好地救治患者。

作为临床研究者，我们扎根临床、直面患者，很多研究灵感都来源于患者，也正是这份牵挂激励我们不断探索，寻找诊疗方案。但一名优秀的医生，首要职责是用心照护每一位就诊患者。然而仅靠救治单个患者，能惠及的人群十分有限。借助临床研究，我们若能探寻更优的诊疗策略，就可以帮助成千上万乃至数百万的患者，其中也包括那些我们未曾面诊的病人。所以临床和科研二者本就是相辅相成的。临床工作中，我们一对一救治患者，这一点至关重要，每一位患者都是需要我们全心对待的独立个体；而科研创新，则能够把诊疗经验放大，惠及更多人群。

Hepatology Digest: Congratulations on receiving the "World Outstanding Chinese Physician Fok YingTung Award". What are your thoughts on this honor, and what does it mean to you? Looking back on your career, what clinical observation or patient experience prompted you to shift from solving individual patients’ problems to designing research that transforms populationlevel clinical practice? How do you understand the relationship between "clinical excellence" and "research innovation"?

Prof. Anna S.F. Lok: First of all, I am deeply honored to receive this award. This honor recognizes my decadeslong work, and it would not have been possible without the support of many colleagues, whose help has shaped my professional career.

It was not any single patient story that inspired my research. My decision to focus on hepatitis B stems from the huge burden this disease places on people in China. Early in my career in Hong Kong, I witnessed many patients suffering from hepatitis B-related cirrhosis and liver cancer in their prime years. This drove me to gain a deeper understanding of the disease so that I could deliver better care.

As clinical researchers, we work closely with patients, and many of our research ideas originate from clinical encounters. This sense of responsibility motivates us to keep exploring and seeking better treatment strategies. The primary duty of a good physician is to care for every individual patient but helping individual patients has limited reach. Through clinical research, if we can identify better therapeutic strategies, we can help thousands and millions of patients, including those we will never meet in clinic. Therefore, clinical practice and research complement each other. In clinical work, we help patients one at a time — and this is critically important, because every patient is an individual who deserves our full attention. Research innovation, by contrast, magnifies clinical insights to benefit far larger populations.

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《国际肝病》：临床卓越要求对患者高度负责，科研创新则要求质疑现有证据、承担不确定性。在繁忙的临床、教学和管理工作中，您如何识别“值得研究的问题”，并把它转化为可执行的研究设计？在密歇根大学，您如何培养年轻肝病医生完成这种从临床到科研的转化？

骆淑芳教授：每个人都有诸多想要推进的工作，但每个人的一天都仅有24小时。这就要求我们明确工作核心、分清轻重缓急，同时保持严谨有序的工作节奏，做好时间与工作的统筹管理。我们始终在努力平衡临床诊疗、教学授课、人才指导与科研攻关等各项工作。

在科研工作中，最关键的是识别出临床上亟待解决的重大难题，以此为核心，设计高效、科学、可落地的研究方案，再依托有序的规划与持续的深耕稳步推进。与此同时，团队力量是科研突破的关键，完善的团队架构能支撑我们完成更多高质量研究工作，这也需要人才培养和导师指导。

在青年医师培养上，我始终秉持因材施教的理念，善于发现年轻人的特长与兴趣点，鼓励他们主动探寻自己真正热爱、愿意深耕的研究方向。究其根本，只有对研究领域怀揣热忱，青年学者才会主动投入时间与精力钻研探索。在科研遭遇瓶颈、进展不顺时，这份发自内心的热爱与专注，也能支撑他们坚守初心、克服困难、不轻言放弃。

想要统筹兼顾各项工作，就必须接受无法一蹴而就、事事并行的现实。我们需要动态判断当下任务，明确工作优先级，制定清晰的工作计划、保持规整的工作节奏。同时要做好团队分工，带领团队成员各司其职、协同协作。

Hepatology Digest: Clinical excellence demands unwavering commitment to patients, while research innovation requires questioning existing evidence and accepting uncertainty. Amid heavy clinical, teaching and administrative responsibilities, how do you identify researchworthy clinical questions and translate them into feasible study designs? At the University of Michigan, how do you train young hepatologists to accomplish this transition from clinical practice to research?

Prof. Anna S.F. Lok: There are countless things we wish to accomplish, yet we only have 24 hours each day. We therefore need to define core priorities, sort out what matters most, and stay wellorganized to manage our time and workload. We constantly strive to balance clinical care, teaching, mentorship and research.

In research, the most critical step is to identify major unmet clinical needs, then develop efficient, scientifically sound and practical study designs, and move the projects forward through structured planning and consistent effort. Meanwhile, teamwork underpins research breakthroughs. A strong team enables highquality work on a larger scale, which requires talent development and mentorship.

When mentoring young physicians, I adopt a studentcentered approach. I seek to discover each trainee’s strengths and interests, and encourage them to pursue topics they are genuinely passionate about. Passion drives young investigators to devote time and energy to indepth exploration, and when research hits roadblocks, that same passion sustains their motivation and keeps them from giving up.

It is unrealistic to accomplish everything all at once when juggling multiple responsibilities. We must assess urgent priorities, draw clear work plans and maintain good organization. We also need to foster proper division of labour within the team, so that members can perform their respective roles collaboratively.

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《国际肝病》：从一线临床医生成长为兼具临床能力与科研产出的学者，途中常会遇到很多瓶颈，您认为青年肝病医师最需要建立的核心能力是什么？

骆淑芳教授：我认为青年医者成长的核心，是明确自身的发展方向与职业目标，在确立目标后制定清晰、可行的行动方案。他们需要一步步落实计划，面对挑战坚持不懈。而一位优秀的导师，能为青年医师提供专业指导、全方位的支持，乃至必要的科研资源，帮助他们保持正确方向、实现目标。

我也常提醒年轻人，医学领域的成功从不是一蹴而就、唾手可得的，唯有脚踏实地、持续深耕，才能有所收获。面对科研受阻、临床遇困等各类挫折与困境时，切忌半途而废。只要坚守初心、坚持不懈、持续深耕，终能突破成长瓶颈，达成自己的职业目标。

Hepatology Digest: Many bottlenecks arise for frontline clinicians as they grow into physicianscientists with both clinical competence and research output. In your view, what core competencies are most essential for young hepatologists to develop?

Prof. Anna S.F. Lok: To me, the cornerstone of young physicians’ professional growth is to clarify career aspirations, set concrete goals, and formulate actionable plans. They need to implement plans stepbystep and persist in the face of challenges. A good mentor can provide professional guidance, comprehensive support and even necessary research resources to help trainees stay on course and reach their goals.

I often remind young people that success in medicine never comes easy. It can only be achieved through sustained hard work. When confronted with setbacks in research or in clinical practice, they should not give up halfway. By staying true to their original aspiration and persevering, they will overcome bottlenecks and reach their professional goals.

（来源：《国际肝病》编辑部）

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